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M.D. Professor of Medicine Birol Vural

Professor of Medicine Birol Vural
+90 850 460 63 34

Hospital Medicana Çamlıca Hospital, Istanbul

Department IVF-Fertility Center

Academic Title Professor of Medicine                                   

Physician Name Birol Vural, M.D. Professor of  Medicine

Graduate Education Hacettepe University School of Medicine (1988)

Postgraduate Education (Residency) Sağlık Bilimleri University Ankara Numune Hospital (1994)

Area of Expertise Infertility and IVF, Endoscopic (Laparoscopic and Hysteroscopic) Surgery, Robotic Surgery, Gynaecology & Obstetrics

Experience Istanbul German Hospital, Assisted Reproductive Techniques Center (1997)

Istanbul American Hospital, Assisted Reproductive Techniques Center (1998)

Assistant Professor  Kocaeli University School of Medicine (1996 -2001)

Associate Professor Kocaeli University School of Medicine (2001 -2009)

Associate Professor Kocaeli Acıbadem Hospital (2009 -2011)

M.D. Professor of Medicine Kocaeli University School of Medicine (2011 -2019)

Medicana Çamlıca Hospital,  Department of IVF - Fertiliy Center, Professor (2019-present)

Publications International

1) Vural B, Mercan R, Çorakçı A, Özeren S, Keskin N, Vural S, Yücesoy İ, Erk A, “A trial of reducing adhesion formation in a uterine horn model,”  Gynecologic and Obstetric Investigation,  45, 58-61 (1998). 

2) Vural B, Cantürk NZ, Esen N, Solakoğlu S, Cantürk Z, Kırkali G, Sökmensüer C, “The role of neutrophils in the formation of peritoneal adhesions,”  Human Reproduction 14, 49-54 (1999).

3) Erk A, Özeren S, Özbay O, Vural B, Elçioğlu N, “ Persistent mullerian duct syndrome: A case report,”  The Journal of Reproductive Medicine,  44, 135-138 (1999).

4) Cantürk NZ, Vural B, Çubukcu A, Düzcen E, Utkan Z, Dülger M, “ Experimental study   on the role of mast cells in peritoneal adhesion formation,”   East African Medical Journal,  76, 233-236 (1999).

5) Vural B, Vural F, Çorakçı A, Türkoğlu S, Erk A, “Does the intrauterine device carry the risk of immunity to sperm ?”  Advances in Contraception,  15, 29-35 (1999). 

6) Vural B, Vural F, Erk A, Karabacak O, “ Knowledge on Lactational Amenorrhea and Contraception in Kocaeli, Turkey,”   East African Medical Journal, 76, 385-389 (1999).  

7) Vural B, Vural F, Diker J, Yücesoy İ, “Factors affecting contraceptive use and behavior in Kocaeli, Turkey,”  Advances in Contraception,15, 325-36 (1999). 

8) Cantürk NZ, Vural B, Esen N, Cantürk Z, Oktay G, Kırkali G, Solakoğlu S, “ Effects of granulocyte-macrophage colony- stimulating factor on incisional wound healing in an experimental diabetic rat model,”  Endocrine Research,  25,105-116 (1999).

9) Vural B, Solakoğlu S, Dalçık H, Vural F, Dalçık C, Erk A,Yücesoy İ, “Antiproliferative effects and insulin-like growth factor-I expression in Balb-C 3T3 fibroblasts after treatment with somatostatin and gonadotropin-releasing hormone analogs,” Acta Histochemica: A Journal of Structural Biochemistry, 102, 353-363 (2000).

10) Cantürk NZ,  Esen N, Vural B, Cantürk Z, Kırkali G, Oktay G, Solakoğlu S, “The relationship between neutrophils and incisional wound healing,” Skin Pharmacology and Applied Skin Physiology,  14, 108-116 (2001).

11) Dalçık H, Yardımoğlu M, Vural B, Dalçık C, Filiz S, Gonca S, Köktürk S, Ceylan S, “ Expression of insulin-like growth factor in the placenta of intrauterine growth-retarded human fetuses,”Acta Histochemica: A journal of Structural Biochemistry,103,195-20(2001).

12) Cantürk NZ, Vural B, Cantürk Z, Esen N, Vural S, Solakoğlu S, Kırkali G, “ The role of L-arginine and neutrophils on incisional wound healing, “   European Journal of Emergency Medicine, 8, 311-315 (2001)

13) Vural B, Çalışkan E, Doğer E, Erçin C. Uterine prolapse in a young nulligravida with scleroderma and premature ovarian failure. International Urogynecology Journal and Pelvic Floor Dysfunction  16(5):415-7 (2005).

14) Dal J, Vural B, Çalışkan E. et al. Power doppler ultrasound studies of ovarian, uterine and endometrial blood flow in regularly menstruating women with respect to luteal phase problems. Fertility and Sterility  84(1):224-7 (2005).

15) Vural F, Vural  B.  First trimester diagnosis of dicephalic parapagus conjoined twins via transvaginal ultrasonography. Journal of Clinical Ultrasound 33(7):364-6 (2005).

16) Vural F, Vural B, Yucesoy I, Badur S. Ovarian aging and bone metabolism in menstruating women aged 35- 50 years. Maturitas  16;52(2):147-53 (2005) 

17) Çalışkan E, Vural B, Turkoz E, Tan O. Conservative management of placenta percreta: Two cases with an emphasis on tubal patency. Gynecological Surgery 2: 29-31 (2005).

18) Yücesoy G, Özkan S, Bodur H, Çalışkan E, Tan T, Vural B, Çorakçı A. Maternal and perinatal outcome in pregnancies complicated with hypertensive disorder of pregnancy: a seven year experience of a tertiary care center. Archives of Gynecology and Obstetrics 273(1):43-9 (2005) 

19) Vural B, Sofuoğlu K,  Çalışkan E, Delikara N,  Aksoy E, Uslu H, Karan A Predictors of intracytoplasmic sperm injection outcome in couples with and without male factor infertility. Clinical and Experimental Obstetrics and Gynecology 32(3):158-62. (2005)

20) Vural B, Özkan S, Yıldız K, Çorakçı A, Gürbüz Y. Malignant fibrous histiocytoma of the vulva: a case report. Archives of Gynecology and Obstetrics 273(2):122-5 (2005)

21) Vural B, Calişkan E, Turkoz E, Kilic T, Demirci A. Evaluation of metabolic syndrome frequency and premature carotid atherosclerosis in young women with polycystic ovary syndrome Hum Reprod. 2005 Sep;20(9):2409-13

22) Vural F, Vural B, Yucesoy I. Reproductive aging and ovarian volume. Int J Gynaecol Obstet. 91(1):73-4 (2005)

23) Vural B, Özkan S, Bodur H. Is Prostate-Specific Antigen A Potential New Marker of Androgen Excess In Polycystic Ovary Syndrome? The Journal Of Obstetrics and Gynecology Research. 33(2):166-73 (2007)

24) Vural B, Özkan S, Çiftçi E, Bodur H, Yücesoy I. Spontaneous vaginal expulsion of an infected necrotic cervical fibroid through a cervical fistula after uterine artery embolization. Journal of Reproductive Medicine.  52(6):563-6 (2007).

25) Özkan S, Vural B, Caliskan E, Bodur H, Turkoz E, Vural F. Colour Doppler Ultrasonographic Analysis Of Uterine And Ovarian Arteries Blood Flow In Women with Polycystic Ovary Syndrome. Journal Of Clinical Ultrasound.  35(6):305-13 (2007).

26) Caliskan E, Filiz T, Yucesoy G, Coskun E, Vural B, Corakci A. Sublingual versus vaginal misoprostol for cervical ripening PRIOR TO manual vacuum aspiration under local anaesthesia: a randomized study. Eur J Contracept Reprod Health Care. 12(4):372-7 (2007) 

27) Özkan S, Vural B, Costur P, Dalcık H, Filiz S. Placental Expression Of Insulin-Like Growth Factor-basic, Fibroblast Growth Factor and Neural Cell Adhesion Molecule In Preeclampsia. J Matern Fatal Neonatal Med. 21(11): 831-8 (2008)

28) Özkan S, Vural B,  Dalcık C, Tas A, Dalcık H. Placental Expression of Insulin-Like Growth Factor-basic, Fibroblast Growth Factor and Neural Cell Adhesion Molecule In Pregnancies with small for gestational age fetuses Journal of Perinatal Medicine. 28 (7); 468-74 (2008)

29) Ozkan S, Caliskan E, Doger E, Yücesoy İ, Özeren S, Vural B. Comparative afficacy and safety of vaginal misoprostol versus dinoprostone vaginal insert in labor induction at term: a randomized trial. Arch Gynecol Obstet.  280(1):19-24 (2009)

30) Ozturk HB, Vural B, Caliskan E, Solakoglu S. Effect of GnRH analogues and octreotide treatment on apoptosis and the cell proliferation of endometrium adenocarcinoma cell lines. J Turkish German Gynecol Assoc, 11: 131-136 (2010) 

31) Bıyıksız PC, Filiz S, Vural B. The Effect of Sildenafil Citrate on IGF-1 and bFGF Expression Acting on Endometrial Receptivity in Controlled Ovarian Hyperstimulated Rats. Turkiye Klinikleri Journal of Medical Sciences. 30(6): 1795-1805 (2010)

32) Bıyıksız PC, Filiz S, Vural B. Is sildenafil citrate affect endometrial receptivity? An immunohistochemical study. Gynecol Endocrinol 27(10): 767-774 (2011) 

33) Cakiroglu Y, Vural B, Isgoren S. The effects of drospirenone-ethinyl estradiol and drospirenone-ethinyl estradiol + metformin on ovarian ultrasonographic markers, body fat mass index, leptin, and ghrelin. Arch Gynecol Obstet.  288(1): 213-220 (2013)

34) Vural B, Cakiroglu Y, Vural F, Filiz S. Hormonal and functional biomarkers in ovarian response. Arch Gynecol Obstet 289(6):1355-61(2014) 

35) Vural F, Çiftçi S , Vural B. The Knowledge, Attitude and Behaviour of Nurses, Working in a State Hospital about Pharmacovigilance, Adverse Drug Reaction and Event Reporting. North Clin Istanbul, 1(3): 147-152 (2014)

36) Vural F, Çiftçi S, Çakıroğlu Y, Vural B. Patient Satisfaction in Outpatient Services: The Evaluation of Service Components by Regression Analysis. North Clin Istanbul, 1(2): 71-77 (2014).

37) Vural F, Vural B, Paksoy N. Vaginal teratoma: A case report and review of the literature. J Obstet Gynaecol 11:1-2 (2015).

38) Vural F, Vural B, and Çakıroğlu Y. The Role of Overweight and Obesity in In Vitro Fertilization Outcomes of Poor Ovarian Responders. Biomed Research International 2015; 2015: 781543. Doi: 10.1155/2015/781543.

39) Vural B, Vural F, Müezzinoğlu B. An Abdominal Wall Desmoid Tumor Mimicking Cesarean Scar endometriomas: A case Report and Review of the Literature. J Clin Diagn Res. 9(9): QD 14-6 (2015).doi: 10.7860/JCDR/2015/14512.6533.

40) Vural F, Yıldırım F, Vural B. The impact of integrated obstetric and neonatal services on utilization of postpartum maternal health care services. North Clin Istanbul.  2 (2): 128-135(2015).

41) Vural F, Vural B, Cakiroglu Y. The effect of Combined Antenatal and Postnatal Counselling on Postpartum Modern Contraceptive Use: Prospective Case-Control Study in Kocaeli, Turkey. J Clin Diagn Res. 10(4):QC04-7 (2016). doi: 10.7860/JCDR/2016/16931.7641.

42) Cakiroglu Y, Vural F, Vural B. The inflammatory markers in polycystic ovary syndrome: association with obesity and IVF outcomes. J Endocrinol Invest 
J Endocrinol Invest. 39(8):899-907 (2016). doi: 10.1007/s40618-016-0446-4. 

43) Vural F, Vural B. The effect of prenatal and postnatal education on exclusive breastfeeding rates. Minerva Pediatrica. 69(1):22-29 (2017) doi: 10.23736/S0026-4946.16.04183-9.

44) Vural B, Çakıroglu Y, Vural F. The predictor marker of ovarian response in poor responders under forty years. Clin Exp Obs&Gyn 43(5):650-653 (2016)

45) Cakiroglu Y, Doger E, Vural F, Kopuk SY, Vural B. Comparison of invitro fertilization outcomes in unoperated unilateral/bilateral endometriomas with operated unilateral/bilateral endometriomas. Journal of Reproductive Medicine (2017).

46) Vural F, Vural B, Çakiroglu Y. In vitro fertilization outcomes in obese women under and above 35 years of age. Clin Exp Obstet Gynecol.43(2):233-7 (2016).

47) Vural F, Vural B, Doğer E, Çakıroğlu Y, Çekmen M. Perifollicular blood flow and its relationship with endometrial vascularity, follicular fluid EG-VEGF, IGF-1, and inhibin-a levels and IVF outcomes.J Assist Reprod Genet.33(10):1355-1362 (2016) 

48) Vural B, Çakıroglu Y, Vural F, Yıldırım SK. Application of a Mixed Material Graft to Posterior Intravaginal Slingoplasty Procedure: Preliminary Pilot Series. J Clin Diagn Res. 11(5):QR01-QR03 (2017).  doi: 10.7860/JCDR/2017/22017.9804. 

49) Cakiroglu Y, Doger E, Vural F, Kopuk SY, Vural B. Impact of insulin resistance and obesity on intracytoplasmic sperm injection outcomes in young women with polycystıc ovary syndrome. North Clin Istanb. 2017 Oct 20;4(3):218-224. doi: 10.14744/nci.2017.79663.

50) Kopuk SY, Çakıroğlu Y, Doğer E, Vural F, Vural B.  Comparison of in Vitro Fertilization Outcomes in Unoperated Unilateral/Bilateral Endometriomas with Operated Unilateral/Bilateral Endometriomas. J Reprod Med. 2017