Faculty of Medicine and Year of Graduation

1994 Çukurova University Faculty of Medicine

Place and Year of Specialization Education

1994-2000 Erciyes University Faculty of Medicine General Surgery

Professional Experience

2000-2002 General Surgery Specialist in Tarsus State Hospitals

2002-2004 General Surgery Specialist in Kayseri State Hospitals

2004 Gazi University Faculty of Medicine / Lecturer

2007 Gazi University Faculty of Medicine / Associate Professor

2013 Gazi University Faculty of Medicine / Professor

2010 Newyork Memorial Slaon Kettering Cancer Center

2014Toronto University Toronto General Hospital

20016 and 2018 Korea Seol ASAN Hospitals Pancreas and Liver Surgery Center

2012-2013 Gazi University Health Practice and Research Hospital Deputy Chief Physician

2014-2015 Gazi University, Director of the Institute of Health Sciences

2015 Ministry of Health Cancer Institute scientific committee member

Secretariat of the 2017 Turkish Hepatopancreatobiliary (HPB) Congress

Medical Area of Interests

Acute pancreatitis

Bile duct cancers

Bile duct stenosis

Chronic pancreatitis

Gall bladder diseases

Gallbladder cancer

Pancreatic Intraductal Papillary Mucosal Neoplasm (IPMN)

Liver cancer

Liver metastasis

Pancreatic cancer

Pancreatic cysts and tumors with cancer risk

Pancreatic cysts

Pancreatic pseudocyst

Scientific Publications

1. Intra-Operative Frozen Section Histology of the Pancreatic Resection Margins and Clinical Outcome of Patients with Adenocarcinoma of the Head of the Pancreas Undergoing Pancreaticoduodenectomy.
Dikmen K, Kerem M, Bostanci H, Sare M, Ekinci O.
Med Sci Monit. 2018 Jul 15;24:4905-4913. doi: 10.12659/MSM.910279.
PMID: 30007990
________________________________________
2. Recombinant adiponectin inhibits inflammation processes via NF-kB pathway in acute pancreatitis.
Dikmen K, Bostanci H, Gobut H, Yavuz A, Alper M, Kerem M.
Bratisl Lek Listy. 2018;119(10):619-624. doi: 10.4149/BLL_2018_110.
PMID: 30345768
________________________________________
3. Prevention of inadvertent injury to aberrant hepatic artery arising from superior mesenteric artery during laparoscopic pancreaticoduodenectomy.
Can MF, Kerem M, Dikmen K.
Turk J Surg. 2018 Aug 31:1-2. doi: 10.5152/turkjsurg.2018.3853. [Epub ahead of print] No abstract available.
PMID: 30216174
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4. Outcomes After Minimally-invasive Versus Open Pancreatoduodenectomy: A Pan-European Propensity Score Matched Study
Klompmaker S, van Hilst J, Wellner UF, Busch OR, Coratti A, D'Hondt M, Dokmak S, Festen S, Kerem M, Khatkov I, Lips DJ, Lombardo C, Luyer M, Manzoni A, Molenaar IQ, Rosso E, Saint-Marc O, Vansteenkiste F, Wittel UA, Bonsing B, Groot Koerkamp B, Abu Hilal M, Fuks D, Poves I, Keck T, Boggi U, Besselink MG; European consortium on Minimally Invasive Pancreatic Surgery (E-MIPS).
Ann Surg. 2018 Jun 1. doi: 10.1097/SLA.0000000000002850. [Epub ahead of print]
PMID: 29864089
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5. A Case Report of Bilateral Adrenal Sarcomatoid Carcinoma.
Turhan Iyidir O, Cerit ET, Özkan Ç, Altınova E, Çimen AR, Sözen S, Kerem M, Aktürk M, Memiş L, Törüner B, Çakır N, Arslan M.
Case Rep Surg. 2016;2016:3768258. doi: 10.1155/2016/3768258. Epub 2016 Dec 20.
PMID: 28097033 Free PMC Article
________________________________________
6. Turkish Ministry of Health, 2nd Turkish Medical General Assembly Clinical Oncology Study Group Report.
Özmen V, Dağoğlu N, Dede İ, Akçakaya A, Kerem M, Göksel F, Özgür E, Başkan E, Yaylacı M, Ceydeli A, Baykara M, Kızıltan HŞ, Kömürcü Ş, Gümüş M, Türk HM, Demirhan R, Akgün A, Kadoglou N, Yatman E, Elbi CC, Güleç S, Soran A, Özet A, Keleştimur F.
J Breast Health. 2016 Jan 1;12(1):9-17. doi: 10.5152/tjbh.2015.2869. eCollection 2016 Jan.
PMID: 28331725 Free PMC Article
________________________________________
7. Increased Resistin Levels in Intra-abdominal Sepsis: Correlation with proinflammatory cytokines and Acute Physiology and Chronic Health Evaluation (APACHE) II scores.
Yilmaz TU, Kerem M, Demirtaş CY, Pasaoǧlu O, Taşcilar O, Sakrak O, Dikmen K, Karahan T.
Sultan Qaboos Univ Med J. 2014 Nov;14(4):e506-12. Epub 2014 Oct 14.
PMID: 25364554 Free PMC Article
________________________________________
8. Extremely high level of CA 19-9 in a patient with metastatic pancreatic cancer: second highest level of CA 19-9 in literature.
Cemal Kizilarslanoglu M, Civelek R, Kemal Kilic M, Kerem M, Gunaydin Y, Ulger S.
J BUON. 2014 Apr-Jun;19(2):583-4. No abstract available.
PMID: 24965432
________________________________________
9. PPAR-alpha agonist treatment increases trefoil factor family-3 expression and attenuates apoptosis in the liver tissue of bile duct-ligated rats.
Karakan T, Kerem M, Cindoruk M, Engin D, Alper M, Akın O.
Turk J Gastroenterol. 2013;24(2):134-40.
PMID: 23934460 Free Article
________________________________________
10. Giant serous microcystic pancreas adenoma.
Dikmen K, Bostanci H, Yildirim AC, Sakrak O, Kerem M.
Rare Tumors. 2012 Oct 10;4(4):e56. doi: 10.4081/rt.2012.e56. Epub 2012 Dec 10.
PMID: 23372920 Free PMC Article
________________________________________
11. Hepatotoxicity associated with lapatinib in an experimental rat model.
Demirci U, Buyukberber S, Yılmaz G, Kerem M, Coskun U, Uner A, Baykara M, Pasaoglu H, Benekli M.
Eur J Cancer. 2012 Jan;48(2):279-85. doi: 10.1016/j.ejca.2011.10.011. Epub 2011 Nov 16. Erratum in: Eur J Cancer. 2013 Feb;49(3):767. Pasali, Hatice [corrected to Pasaoglu, Hatice].
PMID: 22100178
________________________________________
12. The timing of laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreaticography in cholelithiasis coexisting with choledocholithiasis.
Salman B, Yilmaz U, Kerem M, Bedirli A, Sare M, Sakrak O, Tatlicioglu E.
J Hepatobiliary Pancreat Surg. 2009;16(6):832-6. doi: 10.1007/s00534-009-0169-4. Epub 2009 Aug 22.
PMID: 19701600
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13. Administration of Chlorella sp. microalgae reduces endotoxemia, intestinal oxidative stress and bacterial translocation in experimental biliary obstruction.
Bedirli A, Kerem M, Ofluoglu E, Salman B, Katircioglu H, Bedirli N, Yilmazer D, Alper M, Pasaoglu H.
Clin Nutr. 2009 Dec;28(6):674-8. doi: 10.1016/j.clnu.2009.06.001. Epub 2009 Jul 8.
PMID: 19589628
________________________________________
14. Exogenous ghrelin enhances endocrine and exocrine regeneration in pancreatectomized rats.
Kerem M, Salman B, Ozsoy S, Pasaoglu H, Bedirli A, Haziroglu R, Yilmaz TU.
J Gastrointest Surg. 2009 Apr;13(4):775-83. doi: 10.1007/s11605-008-0778-2. Epub 2008 Dec 11.
PMID: 19082668
________________________________________
15. Effects of microalgae Chlorella species crude extracts on intestinal adaptation in experimental short bowel syndrome.
Kerem M, Salman B, Pasaoglu H, Bedirli A, Alper M, Katircioglu H, Atici T, Percin EF, Ofluoglu E.
World J Gastroenterol. 2008 Jul 28;14(28):4512-7.
PMID: 18680231 Free PMC Article
________________________________________
16. Adipokines and ghrelin in gastric cancer cachexia.
Kerem M, Ferahkose Z, Yilmaz UT, Pasaoglu H, Ofluoglu E, Bedirli A, Salman B, Sahin TT, Akin M.
World J Gastroenterol. 2008 Jun 21;14(23):3633-41.
PMID: 18595130 Free PMC Article
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17. Effect of adrenomedullin on hepatic damage in hepatic ischaemia/reperfusion injury in rats.
Kerem M, Bedirli A, Pasaoglu H, Ofluoğlu E, Yilmazer D, Salman B, Yilmaz TU.
Liver Int. 2008 Aug;28(7):972-81. doi: 10.1111/j.1478-3231.2008.01741.x. Epub 2008 Apr 23.
PMID: 18435717
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18. Hepatic energy metabolism and the differential protective effects of sevoflurane and isoflurane anesthesia in a rat hepatic ischemia-reperfusion injury model.
Bedirli N, Ofluoglu E, Kerem M, Utebey G, Alper M, Yilmazer D, Bedirli A, Ozlu O, Pasaoglu H.
Anesth Analg. 2008 Mar;106(3):830-7, table of contents. doi: 10.1213/ane.0b013e3181616fc9.
PMID: 18292427
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19. Wegener's granulomatosis with massive gastrointestinal hemorrhage due to jejunal and colonic involvement: report of a case.
Deger SM, Sahin T, Vural C, Aygencel G, Kerem M, Onal B, Tezel E.
Surg Today. 2008;38(2):166-9. doi: 10.1007/s00595-007-3574-9. Epub 2008 Feb 1.
PMID: 18239879
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20. Infliximab "TNF-alpha antagonist" decreases intraabdominal adhesions.
Kurukahvecioglu O, Koksal H, Gulbahar O, Erdem O, Engin D, Yazicioglu O, Kerem M, Taneri F.
Saudi Med J. 2007 Dec;28(12):1830-5.
PMID: 18060211
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21. Peroxisome proliferators-activated alpha agonist treatment ameliorates hepatic damage in rats with obstructive jaundice: an experimental study.
Cindoruk M, Kerem M, Karakan T, Salman B, Akin O, Alper M, Erdem O, Unal S.
BMC Gastroenterol. 2007 Nov 28;7:44.
PMID: 18045488 Free PMC Article
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22. Coexistence of Mirizzi syndrome with adenomyomatosis in the gallbladder: report of a case.
Bedirli A, Kerem M, Bostanci H, Karakan T, Sahin TT, Akyurek N.
Hepatobiliary Pancreat Dis Int. 2007 Aug;6(4):438-41.
PMID: 17690046 Free Article
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23. Effect of timing of glutamine-enriched enteral nutrition on intestinal damage caused by irradiation.
Salman B, Oguz M, Akmansu M, Bebitoglu I, Akca G, Sultan N, Emre U, Kerem M, Yilmaz U.
Adv Ther. 2007 May-Jun;24(3):648-61.
PMID: 17660176
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24. Ergothioneine modulates proinflammatory cytokines and heat shock protein 70 in mesenteric ischemia and reperfusion injury.
Sakrak O, Kerem M, Bedirli A, Pasaoglu H, Akyurek N, Ofluoglu E, Gültekin FA.
J Surg Res. 2008 Jan;144(1):36-42. Epub 2007 Jul 2.
PMID: 17603080
________________________________________
25. Leptin treatment ameliorates acute lung injury in rats with cerulein-induced acute pancreatitis.
Gultekin FA, Kerem M, Tatlicioglu E, Aricioglu A, Unsal C, Bukan N.
World J Gastroenterol. 2007 Jun 7;13(21):2932-8.
PMID: 17589942 Free PMC Article
________________________________________
26. Beta-glucan attenuates inflammatory cytokine release and prevents acute lung injury in an experimental model of sepsis.
Bedirli A, Kerem M, Pasaoglu H, Akyurek N, Tezcaner T, Elbeg S, Memis L, Sakrak O.
Shock. 2007 Apr;27(4):397-401.
PMID: 17414422
________________________________________
27. Effects of two conventional preoperative radiation schedules on anastomotic healing in the rat colon.
Bedirli A, Kerem M, Karahacioglu E, Ofluoglu E, Yilmaz TU, Pasaoglu H, Tater OP, Sakrak O, Pak Y.
Eur Surg Res. 2007;39(3):141-7. Epub 2007 Mar 2.
PMID: 17337891
________________________________________
28. Role of ghrelin and leptin in predicting the severity of acute pancreatitis.
Kerem M, Bedirli A, Pasaoglu H, Unsal C, Yilmaz TU, Ofluoglu E, Sahin TT.
Dig Dis Sci. 2007 Apr;52(4):950-5. Epub 2007 Feb 27.
PMID: 17333355
________________________________________
29. Spontaneous gastrosplenic fistula in primary gastric lymphoma: Surgical management.
Kerem M, Sakrak O, Yilmaz TU, Gultekin FA, Dursun A, Bedirli A.
Asian J Surg. 2006 Oct;29(4):287-90.
PMID: 17098664 Free Article
________________________________________
30. Ischemic preconditioning improves liver regeneration by sustaining energy metabolism after partial hepatectomy under ischemia in rats.
Kerem M, Bedirli A, Ofluoglu E, Deniz K, Turkozkan N, Pasaoglu H, Sakrak O.
Liver Int. 2006 Oct;26(8):994-9.
PMID: 16953840
________________________________________
31. Effects of soluble fiber on matrix metalloproteinase-2 activity and healing of colon anastomosis in rats given radiotherapy.
Kerem M, Bedirli A, Karahacioglu E, Pasaoglu H, Sahin O, Bayraktar N, Yilmaz TU, Sakrak O, Goksel F, Oguz M.
Clin Nutr. 2006 Aug;25(4):661-70. Epub 2006 May 4.
PMID: 16677740
________________________________________
32. Torsion of the greater omentum: preoperative computed tomographic diagnosis and therapeutic laparoscopy.
Kerem M, Bedirli A, Mentes BB, Sakrak O, Pala I, Oguz M.
JSLS. 2005 Oct-Dec;9(4):494-6.
PMID: 16381377 Free PMC Article
________________________________________
33. Effects of ischemic preconditioning on regenerative capacity of hepatocyte in the ischemically damaged rat livers.
Bedirli A, Kerem M, Pasaoglu H, Erdem O, Ofluoglu E, Sakrak O.
J Surg Res. 2005 May 1;125(1):42-8.
PMID: 15836849

Scientific activities

Türk Hepato-Pankreato-Biliyer Cerrahi Derneği, Antalya Bölgesel Toplantısı, Laparoskopik HPB Kursu 2, 3 Kasım 2018, Antalya, Türkiye, Konuşmacı

2th International Advanced Liver and Pancreas Symposium, ASAN Medical Center, October 4th-6th 2019, Seoul, South Korea.

Speaker: Laparoscopic pancreaticoduodenectomy: Turkey experiences.

6. Ulusal HEBIPA Kongresi, 10-14 Ekim 2018, Antalya, Türkiye, Konuşmacı

Türk HPB Derneği, Kayseri Bölgesel Toplantısı, 29 Eylül 2018, Kayseri, Türkiye, Speaker

13th World International HPB (IHPBA) Congress, 4-7 September, 2018. Geneva, Switzerland, Chair

Türk HPB Derneği, Laparoskopik HPB Kursu 1, 25 Mayıs 2018, Ankara, Turkey, Kurs sorumlusu.

21. Ulusal Cerrahi Kongresi, 11-15 Nisan 2018, Antalya, Türkiye, Konuşmacı

Türk HPB Derneği, İstanbul Bölgesel Toplantısı, 10 Mart 2018, Istanbul, Turkey, Konuşmacı

A-EHPBA ve Türk HPB Derneği çalıştayı: Türki Cumhuriyetler ve yakın ülkeler HPB yapılandırılması. 10 Şubat 2018. İzmir, Türkiye. Konuşmacı

13. Türk HPB Cerrahisi Kongresi, 1-4 Kasım, 2017, Antalya, Türkiye. Kongre Sekterteri, Konuşmacı

1th International Advanced Liver and Pancreas Symposium, September 28-29 2017, Ankara, Türkiye, Konuşmacı

12th World Congress, IHPBA, 20-23 April, Sao Paulo, Brasil, Presenter

12. Türk HPB Cerrahisi Kongresi, 1-4 Nisan 2015, Antalya, Türkiye. Konuşmacı

11th World Congress, IHPBA, March 22-27, Seuol, South Korea, Presenter.

11. Türk HPB Cerrahisi Kongresi, 13-17 Kasım 2013, Antalya, Türkiye, Konuşmacı